The same COVID-19 mRNA vaccine product should be used for both doses of a two-dose primary series and for an additional primary dose if needed. The mRNA vaccines are preferred over Johnson Johnsons Janssen COVID-19 vaccine in most circumstances but the JJJanssen COVID-19 vaccine may be considered in some situations.
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The term hnRNA is often used as a synonym for pre-mRNA although in the strict sense.
. Pre-mRNA is synthesized from a DNA template in the cell nucleus by transcription. Once pre-mRNA has been completely processed it is termed mature messenger RNA or simply messenger RNA. Pre-mRNA comprises the bulk of heterogeneous nuclear RNA hnRNA.
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